Zebrafish MAVS (NM_001080584.2), TBK1 (NM_001044748.2 ... Polyinosinic-polycytidylic acid (poly I:C) was purchased from Sigma-Aldrich used at a final concentration of 1 µg/µl. MG132 (Cat. No. M7449), ...

More recently, zebrafish models have been used to study the interactions between gut microbiota and hosts. It has several advantages, such as short reproductive cycle, low rearing cost, transparent ...

Irf3 and Irf7 initiate the expression of type 1 interferons that further exacerbates the antiviral innate immune response to infection. Table 2 Table of antiviral genes studied in zebrafish models of ...

(B and C) IB of proteins in EPC cells transfected with indicated plasmids for 18 h, followed by treatments of MG132 (10 μM), 3-MA (2 mM), Baf-A1 (100 nM), and CQ (50 μM) for 6 h, respectively. (D) IB ...

Through the use of zebrafish screening and phenotypic analysis in mdx mice and human DMD myoblasts we are in the process of validating the potential for repurposed drugs as a precursor to initiating ...

Swimming in a fishbowl 380 kilometers above Earth, they flipped, spun, and struggled to find their bearings — until they adapted. For 43 days in 2024, four zebrafish orbited China’s Tiangong space ...

Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong Province 518060, China State Key Laboratory of Pollution Control and ...