In this narrative and critical review, we aim to see the potential use of immune cells modulation or cell therapy as therapeutic alternatives to OA patients. Macrophages are immune cells that are ...

Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose tissue dysfunction and contributing to obesity-induced inflammation and metabolic disorders. In this review, ...

the lead drug in Elpiscience’s bispecific macrophage engager (BiME) pipeline. Astellas has licensed rights to ES019 and a second unnamed programme and has also taken an option on up to two ...

PPAR-γ is prominently expressed in activated monocytes and tissue macrophages in vivo, including the foam cells of atherosclerotic lesions 6,7. Multiple functions have been proposed for PPAR-γ ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

1Masonic Cancer Center, Minneapolis, Minnesota. 6Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. 7Department of ...

One of our goals this year is to exponentially grow our multi-omics database, empowering scientists to unlock the potential of public omics data. Take a look at some fascinating colorectal cancer ...

1Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, P ...

Conventional and immunohistochemistry staining were performed on lymph node tissue to assess architecture as well the number of B cells, follicular dendritic cells (FDCs), plasma cells, T cells and ...

It’s not AbbVie’s first foray into T-cell engager dealmaking—the pharma paid $65 million upfront in October to license EvolveImmune’s multispecific biologics for various targets in solid ...