Macrophage infiltration is a hallmark of inflammation, especially in the skin. Although the macrophage response is generally a favorable event in the course of an infection, quite often ...

When there are too many macrophages in a tissue, and they all secrete MCP-1, this can cause inflammation and damage to the tissue. Our findings suggest that blocking the sodium channel or the MCP ...

In a major breakthrough, researchers in the UK have discovered a potential root cause of inflammatory bowel disease (IBD), a ...

UK scientists have made a major breakthrough while investigating inflammatory bowel disease, which could change the lives of ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Discover how atopic dermatitis, an allergic skin condition characterised by inflammation and heightened IgE levels, is often ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells ...

Skin allergies are often worsened by psychological stress, but the underlying mechanisms remain poorly understood.

Richard Staines spoke with Soren Bregenholt, the new CEO of Macrophage Pharma, about the company’s strategy encompassing both immune oncology and inflammatory diseases. In healthy tissues ...

Researchers investigate the cellular and molecular mechanisms through which stress exacerbates immunoglobulin E cutaneous allergic inflammation.