Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

Other macrophage models have been developed but lack certain features unique to alveolar macrophages. The AML model solves both issues by starting with a simple blood draw from donors.

Nanoformulated catalase (nanozyme) obtained by coupling the enzyme to a synthetic polyelectrolyte of opposite charge was loaded into bone marrow macrophages ... in a mouse model of Parkinson's ...

Macrophages are immune cells that reside in ... These changes, in the fibrotic injury model, caused distinct pathways to be activated that led the cells toward a less effective repair, as a ...

According to the Centers for Disease Control and Prevention, more than two in five American adults have obesity, a common and ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

RTX001 is an engineered autologous macrophage cell therapy designed to ... It also plans to evaluate biomarkers, including the Model for End-Stage Liver Disease (MELD) – a scale used to assess ...