The Damon Runyon Cancer Research Foundation has announced eight recipients of the 2025 Damon Runyon-Rachleff Innovation Award, established to support high-risk, high-reward ideas with the potential to ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

A massive trans-ancestry genome-wide association study (GWAS) looked at the genetic makeup of 688,808 individuals with depression and 4,364,225 people in the control group and identified, in total ...

Among the immune cells of the innate and adaptive immune response involved in the pathogenesis of obesity-related diseases, macrophages play a crucial role in the inflammation associated with CKD. In ...

This complex process, known as gene expression, determines which proteins we make and whether we make them in the correct amounts, crucial work given that proteins play a role in virtually every a ...

In a phagocytosis assay using Aβ as a substrate, macrophages isolated after the treatment engulfed less Aβ than did ... Abnormal TSPO values in a child’s blood panel, for instance, could be a tip-off ...

The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can ...

Macrophages, key modulators of immune responses, play a dual role in both promoting and resolving inflammation. Exosomes, small extracellular vesicles released by various cells, carry bioactive ...