中性粒细胞和巨噬细胞是抵御病原体微生物感染的重要免疫细胞。在病原体入侵时，中性粒细胞率先被招募到感染部位，通过吞噬、产生活性氧（ROS）等方式发挥抗菌作用，同时其释放的 NETs 也备受关注。NETs 由双链 DNA、组蛋白和非组蛋白蛋白质组成，在调节免疫反应中发挥重要作用。巨噬细胞则可分化为 M1 和 M2 两种类型，M1 型巨噬细胞分泌促炎细胞因子，增强免疫反应；M2 ...

肝脏巨噬细胞在调节肝细胞代谢和维持肝脏免疫耐受方面发挥核心作用。正常生理条件下，肝脏巨噬细胞倾向于 M2 表型，可通过分泌白细胞介素（IL）-4 和 IL-13 抑制炎症。然而，在 NAFLD 进展时，肝星状细胞激活、血液中脂多糖水平升高以及 FFA 激活炎症小体等变化，会刺激炎症发生，增加分泌促炎细胞因子的 M1 巨噬细胞比例。

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

Spinal cord injury (SCI) is characterized by the temporary or permanent loss of motion or sensation function caused by damage to the spinal cord. Among the mechanisms behind SCI, neuroinflammation is ...

Welcome to Sportstar’s live coverage of the second Vijay Hazare Trophy semifinal between Vidarbha and Maharashtra. Stay tuned for live scores and updates from the game.

Discover the key differences between WebStorm and VS Code, including features, performance, and pricing, to choose the ideal tool for your development needs. WebStorm and Visual Studio Code target ...

PAK vs WI: Pakistan and West Indies are set to clash in their last Test series of the World Test Championship 2025 cycle in Multan starting on January 17. Both teams enter this two-match series ...

Using lineage tracing, we find that tissue-resident red pulp macrophages (RPM), initially depleted by BCG exposure, are restored from both tissue-trained, self-renewing macrophages and from bone ...

Respiratory syncytial virus (RSV) causes cold-like symptoms in most people but can cause more serious problems in some, especially babies and older adults. Almost all children get RSV at least once by ...

Goal! Barcelona 5, Real Betis 1. Vitor Roque (Real Betis) converts the penalty with a right footed shot to the centre of the goal. Attempt saved. Vitor Roque (Real Betis) right footed shot from ...

Match report and free highlights as David Moyes' second reign as Everton manager starts in defeat courtesy of Ollie Watkins' ninth Premier League goal of the season; Toffees remain 16th just a ...

A familiar, craggy face returns to the home dugout at Goodison Park today, as David Moyes begins his second stint in charge of Everton with a tough home game against Aston Villa in the English ...