Canine mast cell tumors (MCTs) are a significant concern in veterinary oncology, representing the most common malignant skin tumors in dogs. These tumors arise from mast cells, which are a type of ...

Recent research has focused on understanding the complex biology of mast cells, their interactions with other cells, and their roles in various diseases, including allergies, asthma, and cancer.

The ketogenic diet has proven to be useful in mast cell tumors, but many other types of cancer need to be investigated. In ...

Many households consider their dogs and cats as integral family members ... particularly for mast cell tumors, reflecting heightened demand for targeted therapeutics that minimize toxicity.

Japan’s pet cancer therapeutics sector surges forward, propelled by evolving diagnostic tools, innovative drug breakthroughs, ...

Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling. Nature Cancer , 2025; DOI: 10.1038/s43018-024-00882-2 Cite This Page : ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Breast cancer metastases are initiated by cancer cells that detach from the primary tumor and migrate to other organs via the bloodstream. These circulating cancer cells (CTCs) are extremely rare ...

The findings are published in Science Advances in an article titled, “Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells.” ...

This is a useful report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...

A brain tumor is a mass of abnormal cells that grow in the brain. Brain tumors can be benign (non-cancerous) or malignant (cancerous) and can start anywhere in the brain. Malignant tumors grow rapidly ...