Reduced insulin secretion leads to elevated blood glucose levels and an increased risk of serious complications, such as cardiovascular disease and nerve damage. The exact mechanisms behind ...

In obesity and insulin resistance, increased secretion of proinflammatory cytokines ... has been associated with antiatherogenic mechanisms, whereas endothelium-derived vasoconstrictors, for ...

Researchers from Lund University, in collaboration with Newcastle University, have uncovered a potential breakthrough in ...

A particular protein commonly found in people with type 2 diabetes can affect insulin secretion among those with the condition, a new study has identified. Researchers from Lund University and ...

Zhen Huang, and Åke Sjöholm. "Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via NO and vagally mediated mechanisms" ...

Impairment of insulin secretion and defects in insulin action ... production of polyol compounds from glucose are among the mechanisms thought to produce tissue damage from chronic hyperglycemia.

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion ... is an important mechanism for glucose ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...