This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Here we review current knowledge of the roles of lipid metabolism and function in the CNS and discuss how modulating these pathways may offer novel therapeutic options for treating ALS. Lipids are ...

In this paper, we review the current state of knowledge on the metabolic phenotypes of prostate cancer. Figure 1. Regulated metabolic pathways involved in energy production and maintenance of ...

The skewed metabolism in the overactivated kynurenine pathway is associated with a relative deficiency in the anti-inflammatory ... KYNA and XANA were administered daily by oral gavage (400 mg/kg and ...

Metabolic pathway enrichment was accomplished via MetaboAnalyst V.5.0.28 GraphPad Prism V.9.0 (GraphPad Software) was used for statistical treatment. Experimental data was shown as mean±SEM.

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Six Sigma is a quality management methodology used to help businesses improve current processes, products, or services by discovering and eliminating defects. The goal is to streamline quality ...

Metabolic Atlas is a project at the National Bioinformatics Infrastructure Sweden, under the scientific direction of Prof. Jens Nielsen at Chalmers University.

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Metabolism comprises a series of interconnected pathways that can function in the presence or absence of oxygen. Aerobic metabolism converts one glucose molecule into 30-32 ATP molecules.

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...