Despite such growth, there remains a set of complex hurdles associated with drug development for rare metabolic diseases. Inborn Errors of Metabolism Drug Development 2020 is dedicated to ...
Metabolism in cancer cells differs from that in normal cells, but it is only recently that opportunities to specifically target these differences to develop novel anticancer drugs are being revealed.
Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown ...
Many genetic variants in drug metabolizing enzymes and transporters have been shown to be relevant for treating psychiatric disorders. Associations are strong enough to feature on drug labels and for ...
A well-known class of drugs used to manage type 2 diabetes and control weight could offer hope for patients who also struggle with related chronic kidney disease (CKD), researchers at UT ...
precise regulation of lipid metabolism (e.g., targeting cholesterol metabolism in a specific cell type) will be feasibility, though there are still many unknowns to be explored, for example, to ...