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CD206靶向肽:CSPGAKVRC
M2型肿瘤相关巨噬细胞与肿瘤细胞分化程度显著相关, 是乳腺癌、胶质母细胞瘤和胃癌等恶性肿瘤增殖和转移的重要标志物. CD206是M2型巨噬细胞特异性的检测靶点, Teesalu等通过噬菌体展示技术筛选了靶向CD206的多肽CSPGAKVRC (UNO). FAM修饰的UNO与CD206抗体共定位成像小鼠 ...
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