Microglia are challenging to identify as most fluorescent labeling approaches cross-react with other immune cell types, are often insensitive to activation state, and require the use of multiple ...

Explore the potential of monoclonal antibodies in Alzheimer’s treatment, including breakthroughs and challenges in this ...

Cells were incubated with the primary antibodies anti-CD11b-FITC (Biolegend cat ... Additionally, our protocol incorporates microglia to more fully recapitulate the cell types present in the brain. In ...

Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.

Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal ...

Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan Division of Molecular Neuroimmunology, Medical Institute of Bioregulation ...

To determine whether neonatal glial cells in culture also express IL-17RA at the protein level we labeled purified astrocytes and microglia with commercially available anti-IL-17R antibody raised ...