This work represents a novel and significant contribution to the field, revealing for the first time that the loss of mitochondria from axons can lead to impaired autophagy function via eIF2β, ...

In flies defective for axonal transport of mitochondria, the authors report the upregulation of one subunit, the beta subunit, of the heterotrimeric eIF2 complex via mass spectroscopy proteome ...

1 Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China 2 Zigong Hospital of Traditional Chinese Medicine, Zigong, China Mitochondria are important organelles that regulate ...

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...

A recent study suggests that when good mitochondria go bad, the activation of both glycolysis and autophagy may permit cellular survival. In most schools, students tend to stratify into groups ...

This process, known as autophagy, is like a self-cleaning mechanism for cells, ... Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no ...

Background: Mitochondria, as the energy factories of cells, are involved in a wide range of vital activities, including cell differentiation, signal transduction, the cell cycle, and apoptosis, while ...

Autophagy loss increases PC vulnerability, independent of its role in protein and mitochondria quality control. Credit: Nature Metabolism (2025). DOI: 10.1038/s42255-024-01196-4 ...

While autophagy is relevant to many biological processes and often serves as a gatekeeper of homeostasis, when something goes wrong it can either lead to disease or be activated to fight against it.

A study published by the Journal of Traditional and Complementary Medicine and e-published by the U.S. National Library of ...