Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...
Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...
Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.
A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...
Additionally, safranin fluorescence assays were conducted further to confirm the elevated membrane potential in the mutant mitochondria and compare it to that of the wild-type and complemented lines.