Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...
Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.
Additionally, safranin fluorescence assays were conducted further to confirm the elevated membrane potential in the mutant mitochondria and compare it to that of the wild-type and complemented lines.