Mayo Clinic has joined SeaStar Medical as the 15th site authorised to enrol subjects for the company’s pivotal NEUTRALIZE-AKI ...
In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.
Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...
Decidual inflammation was found to be a critical pathogenesis of OAPS, but the characteristic and regulator was unrevealed. We found significant monocyte/macrophage infiltration in decidua of OAPS ...
Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...
Used clinically since the 1920s, corticosteroids interrupt multiple steps in immune activation because of ... Lymphocyte, monocyte, and basophil counts decrease in response to corticosteroid ...
Objective Infection with hepatitis B virus (HBV) remains a major cause of liver cirrhosis (LC) in China. Recent reports suggest that the lymphocyte-to-monocyte ratio (LMR) is a potential biomarker for ...
1 2 The group suggests that peripheral blood mononuclear cells (PBMC) are a source of interleukin (IL)-1β in acute decompensation (AD) independent of the canonical inflammasome activation pathway.1 ...
SeaStar Medical plans to conduct an interim analysis at the trial’s 90-day primary endpoint with the first 100 subjects. Given the current pace of enrollment, the company anticipates a Data Safety ...