Whereas dendritic cells are critical for kickstarting the cancer immunity cycle in the lymph node, both dendritic cells and monocytes are needed to fully activate T cells in the tumor. The ...
Treatment with TNF-α (2.5, 5 or 10 ng/ml) or lipopolysaccharide (0.5, 1 or 5 μg/ml) treatment was carried out for 12 h to activate the HUVECs, then 5 × 10 5 fluorescently labeled THP1 monocytes were ...
Study: Cancer cells impair monocyte-mediated T-cell stimulation to evade immunity. Image Credit: CI Photos / Shutterstock.com In a recent study published in Nature, researchers investigate how ...