Objective Infection with hepatitis B virus (HBV) remains a major cause of liver cirrhosis (LC) in China. Recent reports suggest that the lymphocyte-to-monocyte ratio (LMR) is a potential biomarker for ...

Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

The authors present solid evidence for its increased expression in stimulated monocytes/macrophages, its direct bactericidal functions, as well as its role in the modulation of monocyte ...

In this study, the function of JAKs in DCs was investigated with tofacitinib. Methods The effects of tofacitinib on the maturation of human monocyte-derived DCs induced by lipopolysaccharide (LPS) ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

Discover how atopic dermatitis, an allergic skin condition characterised by inflammation and heightened IgE levels, is often ...

Also, the effects of corticosteroids on circulating monocytes and monocyte-macrophage functions are important in the mechanism of immunosuppression. Figure 2 illustrates the anti-inflammatory and ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...