On the other hand, disturbed monocyte function is associated with "immune paralysis". In this condition, the immune system's ability to fight off invaders such as viruses and bacteria is inhibited.

We discuss what monocytes and macrophages are, how they are generated, their functions in the body and conditions related to them. More than 100 years ago, Nobel prize-winning German physician and ...

It is a major area of interest (to which I contribute through my own research), and today a significant number of medications target the immune system to unlock its anti-tumor potential. Interestingly ...

Antibodies are a vital part of the immune system, playing a key role in our ability to fight infection and in the efficacy of vaccinations. However, that’s not where their utility ends. Find out about ...

Caption Illustration shows the new function of blood monocytes, namely their ability to proliferate in tissues before differentiating into macrophages, immune cells that play important roles in ...

The pervasive influence of the immune system on human health and disease underscores the importance of a mechanistic ... We were also the first to report that tumor growth induces monocyte-derived ...

Discover how atopic dermatitis, an allergic skin condition characterised by inflammation and heightened IgE levels, is often ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.