Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Bonus Aug 03, 2007 Aug 06, 2007 Apr 30, 2007 Bonus Ratio: 1 share(s) for every 1 shares held Bonus Aug 06, 2004 Aug 09, 2004 Apr 24, 2004 Bonus Ratio: 1 share(s) for every 1 shares held Bonus Sep 17, ...

Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

Lymphocyte, monocyte, and basophil counts decrease in ... the steroid-receptor complex translocates into the nucleus of the cell, where it attaches to DNA and causes transcription of specific ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

Objective Patients with increased PD-L1 + host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is ...

Circadian rhythms are controlled centrally by the suprachiasmatic nucleus, and are most strongly infuenced by light.

The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

Introduction: Breast cancer is the most common form of cancer diagnosed worldwide and the leading cause of death in women globally, according to Globocan 2020. Hence, investigating novel pathways ...

3 Interdepartmental Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, Italy Blau syndrome (BS) and early-onset ...