Introduction: Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic ...

Emerging evidence reveals that macrophage shift can be determined by several stimuli, apart from the conventional in vitro IL-4, IL-13, and IL-10. Evidences show the potential of physical exercise to ...

Monocytes were isolated by adherence to plastic six well culture plates. After removal of non-adherent cells, the monocytes were differentiated into macrophages in seven days. PAD mRNA expression was ...

We found that CCR2+ cells are abundant in human OA synovium and that CCR2+ macrophages line, invade and are associated with the erosion of OA cartilage. Further, blockade of CCL2/CCR2 signalling ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

“We will take a broader look at where macrophage technology is important in human disease and then apply the technology to that rather than staying specifically within immune oncology.

SINGAPORE: Research from Duke-NUS Medical School has found that foetuses have a functional immune system capable of fighting ...

By exposing microplastics to human immune cells, she observed that a cell type called monocytes was taking up a bit of the plastic itself. Her next step was to develop a 3D cell culture called a ...

Jan. 30, 2025 — The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was ...