Perforin forms transmembrane pores in the plasma membrane, allowing granzymes to enter the target cell cytosol and trigger ...

This important study reveals a new mechanism for gene regulation in neurons by an RNA binding protein called RBM20 previously studied in the heart. The methods used are compelling, including the ...

Numerous court decisions over the past decade – such as Amgen Inc. v. Sanofi from the US Supreme Court and Juno Therapeutics, Inc. et al. v.

Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is ...

This repository contains the source code and associated resources developed for the research paper titled “Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the ...

This article shows how and where to download mouse drivers on Windows 11/10 for Razer, Logitech, Corsair, Dell, ASUS, HP, Microsoft and other mouse brands. How do I add a mouse on Windows 11?

Diverse antibody repertoires spanning multiple lymphoid organs (i.e., bone marrow ... All 36 IgG+ samples were processed and sequenced in three batches of 12 samples by preparing sequencing libraries ...

By comparing this with existing published information from mouse and monkey embryos, they established the timing and sequence of the molecular signals needed to create notochord tissue.

Additionally, the antibody proved “consistent across subgroups” and appeared well tolerated in both IBD conditions with no safety signals identified, according to the partners. Overall rates ...

This helps support our journalism. Learn more. Please also consider subscribing to WIRED Normally, antibodies are protective proteins produced by our immune systems to fight bacteria or viruses.

Scientists in New Zealand blame waning antibody levels. Antibody responses in 150 regular blood donors were measured across the pandemic’s first three years for immunity against a range of ...