Freshly isolated NK cells, but not natural killer T cells or ... of a new member of the TNF family that induces apoptosis. Immunity 3, 673–682 (1995).

Moreover, researchers are investigating ways to enhance the cytotoxic capabilities of NK cells. For instance, studies have shown that targeting the mitochondrial apoptosis pathway can ...

Cellular senescence is a process that leads to a state of irreversible cell growth arrest induced by a variety of intrinsic and extrinsic ... described the significance of regulation of senescence and ...

Activation of this receptor triggers a self-destruction process of cancer cells, known as apoptosis. This approach has shown superior efficacy compared to antibodies targeting DR5, previously ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...

For the new therapy, these cells are derived from stem cells that originated from healthy adult donor tissue - called induced pluripotent stem cells (iPSCs) - to make therapeutic CAR-NK cells.

NK Cells Expressing Interleukin-21 Show Promising ... has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell death called ...

When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis ... the team used sEVs made by natural killer (NK) cells, a type of immune cell that frequently ...

Scientists from the University of Pennsylvania have developed an innovative cancer treatment using small extracellular ...