Introduction: Metastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic ...

Freshly isolated NK cells, but not natural killer T cells or ordinary T cells, from the liver expressed cell surface TRAIL, which was responsible for spontaneous cytotoxicity against TRAIL ...

told the conference that her lab has been able to make natural killer cells targeting CD19, a biomarker found on the surface of certain blood cancer cells. Unmodified natural killer (NK ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

EO771 tumor resection and metastasis model for NK cell treatment. (A) Positive correlation between primary tumor weight and lung metastasis. Pearson correlations between day 21 tumor weights and the ...

Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...

For the new therapy, these cells are derived from stem cells that originated from healthy adult donor tissue - called induced pluripotent stem cells (iPSCs) - to make therapeutic CAR-NK cells.

The team have shown that their nanostructured surfaces resist the growth of bacteria, but enable the culturing of cells. Credit: Tokyo Metropolitan University New nanostructured alumina surfaces offer ...

1Masonic Cancer Center, Minneapolis, Minnesota. 6Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. 7Department of ...

Opens in a new tab or window An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well tolerated both as monotherapy and in combination with rituximab among ...