Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

Unmodified natural killer (NK) cells work differently from the T-cells upon which CAR-T therapies are based – NKs are usually involved in killing cells that are infected with viruses, whereas T ...

Fate Therapeutics uses iPSC and gene editing to offer scalable off-the-shelf therapies. Read more to see why I rate FATE ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Conclusions: Our study shows clear differences in the intrahepatic expression of ICMs on NK cells and T cells in chronic HBV patients depending on their clinical stage. Hepatitis B is one of the most ...

The first patient with relapsed/refractory acute myeloid leukemia has received KJ-C2320, an allogeneic CAR T-cell therapy ...

Freshly isolated NK cells, but not natural killer T cells or ordinary T cells, from the liver expressed cell surface TRAIL, which was responsible for spontaneous cytotoxicity against TRAIL ...

Similar to both αβ T cells and natural killer (NK) cells, γδ T cells express NKG2D which can detect stress-induced signals on tumors and infected cells (4). In addition, these cells also share other ...

NK cells are emerging as a potentially safer and more convenient alternative to the current generation of CAR-T cell therapies – which include Gilead/Kite's Yescarta (axicabtagene ciloleucel ...

The main difference between these CAR-NK cells and the FDA-approved CAR-T cell products lies in the ease of manufacturing. Currently, 10-20% of patients who need CAR-T cell therapy can't access ...

About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a ...