The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...

Canonically, the metabolic depletion of tryptophan and/or the accumulation of kynurenine is the mechanism that defines how immunosuppressive IDO inhibits immune cell effector functions and/or ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

Even though there are indications of the health-promoting and cell-protective properties of ergothioneine, the underlying mechanism of action was previously unknown. "Our analyses now finally ...

It's hard to describe the amazing caliber of the greatest action movies on display during the 1990s for those who weren't around to see it. The decade was more than snap bracelets, pastel polos ...

Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and vitamin K. Protein kinase R-like ...

2025 has a full slate of action movies, each more exciting than the next. The genre has never been more popular, and luckily for audiences, creatives and producers know it. Action is also ...

Netflix’s action movie selection is so stacked, it’s a cinematic adrenaline shot. Even if you don’t typically go for high-octane thrills, there's something on offer that'll have you gripping ...

But sometimes you don’t want that! Sometimes you just want to escape the increasingly insane world out there into an action movie. Netflix has made a few of their own, but the bulk of the best ...

Of all the action cameras we’ve tested, the best make it easy to capture sharp, stable video in all conditions. That doesn’t mean they’re all the same: some are simple and affordable ...