There is involvement of the outer retinal layers (arrowhead) as well with localized atrophy of the retinal pigment epithelium. SDOCT indicates spectral domain optical coherence tomography.

[36] In the acute lesions, a localized, fuzzy area of hyper-reflectivity is seen in the outer retinal layers involving the RPE, photoreceptor outer segment tips, photoreceptor inner segment ...

Their work demonstrated a significant reduction in retinal electrophysiological a-wave and b-wave responses and a marked decrease in the thickness of the outer nuclear layer (ONL) in RD mice ...