Formalin-fixed pancreatic tissue from human tissue specimens and in vivo experiments in mice were subjected to immunohistochemical (IHC) analysis following staining with Ab against IL-6 (Abcam and ...
尽管目前尚未有三抗药物获批,但已有多家生物医药企业布局三特异性抗体,并研发设计出具有迭代优势的靶点组合药物。据不完全统计,目前全球三抗药物管线已超百条,其中约有一半已进入临床阶段,只是大多数尚处于临床早期阶段。
In this study, we demonstrate the feasibility of generating virtual stains for hematoxylin and eosin (H&E) and a multiplex immunofluorescence (mIF) immuno-oncology panel (DAPI, PanCK, PD-L1, CD3, and ...
Introduction: To design effective small molecule inhibitors targeting the immune checkpoint PD-1/PD-L1 and to explore their inhibitory activity. Methods: In this paper, a total of 69 PD-1/PD-L1 ...
欢迎关注凯莱英药闻今日,宜联生物宣布,公司与阿斯利康建立临床研究合作,共同探索YL201(靶向B7H3的抗体偶联药物)与度伐利尤单抗(抗PD-L1免疫检查点抑制剂)联用,治疗多种实体瘤的潜力。双方将共同启动一项多中心、开放性、I/Ib期研究,旨在评估 ...
1月20日,通化东宝发布业绩预告,预计2024年年度实现归属于上市公司股东的净利润约为4052.77万元,与上年同期相比,将减少约11.27亿元,同比减少约96.53%。业绩变动主要原因是,报告期内,新一轮胰岛素集采在全国各省市开始陆续落地实施,公司各胰岛素产品中标价格均有不同程度下降,导致销售收入下滑。
After hours: January 23 at 6:01:26 PM EST ...