[78] Several potent non-selective tyrosine kinase inhibitors that interrupt both VEGF and PDGF signaling have been approved for cancer therapy: imatinib, sorafenib, pazopanib, sunitinib ...

Spatial transcriptomics was combined with single-nucleus RNA sequencing to annotate healthy and fibrotic human livers, improving spatial resolution of hepatocytes and receptor-ligand interactions ...

In the subarachnoid space, CTGF contributes to pia mater fibrosis by promoting the synthesis and deposition of extracellular matrix components. In the non-canonical Smad signaling pathway, the ...

The aim of this study is to investigate the role of somatostatinergic and cytokine signalling in hepatic stellate cells (HSC), the effector cells of hepatic fibrosis. Methods The production of ...

TSP-1 mRNA and protein were detected in quiescent and activated cultured hepatic stellate cells (HSC) and TSP-1 expression was highly inducible by platelet derived growth factor BB (PDGF-BB) and, to a ...

Background: Severe Community-Acquired Pneumonia (SCAP) is a serious global health issue with high incidence and mortality rates. In recent years, the role of biomarkers such as Connective Tissue ...

同时，伤口愈合市场在研发、工艺、临床以及初始投入方面有非常高的门槛，作为目前港股市场唯一一家聚焦PDGF药物研发的稀缺标的，华芢生物将 ...

The S&P 500 finishes the year 23.5% higher, bolstered by strong corporate profits and artificial intelligence investment and enthusiasm. LPL Research expects stocks to move higher in 2025, but ...

According to the daily charts, this exchange-traded fund with a high dividend yield of 3.67% has been under pressure as it has fallen below its short-term moving averages in the oversold territory.

The study provides valuable insights into the mechanisms underlying neurovascular coupling; the authors present solid evidence demonstrating that layer II/III pyramidal neurons can induce ...