One significant area of research focuses on the PDGF/PDGFR signaling pathway and its implications in cancer. Studies have shown that many cancers express PDGFs and their receptors, which can ...
[78] Several potent non-selective tyrosine kinase inhibitors that interrupt both VEGF and PDGF signaling have been approved for cancer therapy: imatinib, sorafenib, pazopanib, sunitinib ...
Antiatherogenic aspects of insulin action include stimulation of NO production, counteraction of VEGF and PDGF effects ... both the MAP-kinase signaling pathway and excessive prenylation of ...
Taking advantage of the urchin genome project, genes involved in PDGF signaling and the synthesis/modification ... We recently discovered evidence that a signaling pathway involving the protein ...