Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

suggest that the therapy can restore the physiological activity of the insulin-producing islet cells of the pancreas and restore glucose control. The study enrolled 17 people with type 1 diabetes ...

This important study investigates the signaling pathways regulating retinal regeneration ... and hollow arrow-heads indicate proliferating NIRG cells (a). The calibration bar represents 50 µm.

The liver and pancreas are the main actors in glucose metabolism, but not the only ones. Muscles, adipose tissue and the brain play different roles. However, the prize for the best new actor in ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.

Types of cell signalling pathways include checkpoint signalling, lipid signalling, growth signalling, nutrient signalling, insulin signalling, stress signalling, morphogen signalling, Hippo ...

IL-1 activity on both DCs and T cells can further shape the adaptive immune response with variable outcomes. IL-1 signaling in DCs promotes their ability to induce T cell activation, but also direct ...

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia ...

TNF-α and granzyme B. The γδ T cells expanded with feeder cells, PHA, IL-2, IL-7 and IL-15 effectively kill target cells Pre-treatment of target cells with PAM improves HAP1 cell killing by Vδ2 T ...

Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves ...

Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this ... When the protein is not working correctly, it’s unable to ...