While pancreatic ... immuno-regulatory pathways, suggesting that cell death regulates the crosstalk with immune cells. Consistently, inhibiting beta-cell death during development reduces ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

Browse 150+ cell signaling pathway stock videos and clips available to use in your projects, or start a new search to explore more stock footage and b-roll video clips. A black man walks through the ...

It is common for a person who has undergone a pancreatectomy to develop diabetes because of loss of the insulin and glucagon hormone-producing cells in the pancreas. Medical researchers are ...

Conceptual diagram summarizing the central experiment comparing cell death in amyloid-β treated neuronal cells with and without pancreatic β cell culture supernatant. Pancreas cells may produce ...

First-in-Human Study Provides Evidence that Sana’s Hypoimmune (HIP) Technology Enables Transplanted Islet Cells to Avoid Immune Rejection and Produce Insulin Without Immunosuppression Results ...

suggest that the therapy can restore the physiological activity of the insulin-producing islet cells of the pancreas and restore glucose control. The study enrolled 17 people with type 1 diabetes ...

Sana’s most advanced programs utilizing this platform include stem cell-derived pancreatic islet cells for patients with type 1 diabetes, an allogeneic CAR T program for B-cell mediated autoimmune ...

Furthermore, ML385, an NRF2 inhibitor, reversed these effects of EUG. The present study suggested that EUG exerted protective effects on pancreatic β cells in T1DM by attenuating apoptosis and ...

The clinical data are highly promising for patients and provide the first evidence in humans for overcoming allogeneic and autoimmune rejection with pancreatic islet cell transplantation in type 1 ...