PACAP is a neuropeptide involved in stress regulation, and the authors studied neurons in a part of the brain called the parabrachial nucleus that produce PACAP and project to the dorsal raphe ...

Key findings show the lateral parabrachial nucleus significantly influences pain processing and response while signals from the lateral hypothalamus can reduce pain responses. These insights could ...

The study found that a brain region called the lateral parabrachial nucleus (LPBN) plays a key role in managing this heightened sensitivity. When the researchers activated LPBN neurons ...