By late 1957 no less than 88% of Staph aureus cultures there were resistant to penicillin, 82% to tetra-cyclihe, and 70% were immune to attack by a combination of the two drugs. Then Dr.

of tetracycline per milliliter. All the organisms were sensitive to penicillin. Disk-sensitivity studies also indicated resistance of strains C.M.R. and G.S. to tetracycline. Table 1 Antibiotic ...

multicenter adult trials comparing daptomycin with either vancomycin or a penicillinase-resistant penicillin. Clinical and microbiological outcomes were similar between daptomycin and the comparator.

BATCH is a national research trial to tackle antibiotic overuse in hospitalised children and reduce the spread of antimicrobial resistance (AMR). Antibiotic overuse is a key driver of AMR ...

Six of 10 blood cultures were positive for a coagulase-positive penicillin-resistant Staph. aureus. The hospital course is summarized in Figure 1. Because of an allergic reaction to penicillin in ...

Beta-lactam antibiotics are the most widely used group of antibiotics, they target the penicillin-binding proteins (PBPs), eventually disrupting the peptidoglycan synthesis. To combat these ...