This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

toward an M1 phenotype. In addition to direct phagocytosis of tumor cells, CAR-M present a patient’s unique array of neoantigens to T cells, leading to a broad adaptive immune response that has ...

Many receptors are involved in this process, some with signalling capabilities, some without. Increasing evidence now shows a previously unappreciated regulatory component to phagocytosis exerted by ...

Background Bacterial infection is a common complication in patients with advanced disease, including cancer. Ingestion (phagocytosis) and subsequent killing of bacteria by neutrophils and monocytes ...