This developmental plasticity requires a strict temporal and spatial control of the cell cycle. Cell-cycle activation in quiescent cells is correlated with a change in chromatin structure and ...

Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and contributing significantly to cancer-related mortality globally. Despite ...

Thanks to Rice researchers' new findings, however, phosphorylation-based innovations in "smart cell" engineering could ... set out to prove -- was that each cycle in a cascade can be treated ...

However, the combination of AZD4547 and nab-PTX suppressed the phosphorylation of the MAPK signaling pathway, which led to cell cycle arrest in the G2/M phase, promoted apoptosis, and exerted a ...

Thanks to Rice researchers' new findings, however, phosphorylation-based innovations in "smart cell" engineering could ... set out to prove—was that each cycle in a cascade can be treated ...

Furthermore, the signaling metabolites succinate and itaconate can accumulate independently of characteristic breaks in the TCA cycle in mouse and human macrophages, and peritoneal macrophages can be ...

Thanks to Rice researchers’ new findings, however, phosphorylation-based innovations in “smart cell” engineering ... out to prove — was that each cycle in a cascade can be treated as ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

Phosphoproteomics unveils the mode of action of clinical ATR inhibitors and explains their synergy with Gemcitabine in ...