Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.
Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...
Featured pricing is subject to change. We know the feeling — the feeling of waltzing down a supermarket aisle to find the best protein bars, but getting too overwhelmed that we just put our ...
A new study reveals the potential of two compounds in treating retinitis pigmentosa, a blinding genetic disorder. These compounds, identified through virtual screening, have shown promising results in ...
For protein studies, we evaluated RPE cells by immunocytochemistry using a rabbit anti-RPE65 peptide polyclonal antibody (provided by T.M. Redmond). For western-blot analysis, proteins from ...
Structural and chemical instability of naked, nonmodified nucleic acids • Availability of conclusive biochemical or in vivo assays for protein activity • Design and selection • Complex folding ...