Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive form of blood cancer that primarily affects older adults. It is characterized by the proliferation of precursors of ...

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.

Plasmacytoid urothelial carcinoma is rare and aggressive ... Urothelial cancer has benefited from lab-based research in mouse models, in organoids, and in cell cultures of urothelial carcinoma, where ...

Background: Both plasmacytoid dendritic cells (pDCs) and B cells play pivotal roles in various autoimmune diseases, such as systemic lupus erythematosus (SLE), systemic sclerosis, and rheumatoid ...

Dendritic cells (DC) offer hope that the treatment of end-stage cancer will become much more successful in the near future. Hundreds of dendritic cell-based therapeutic vaccines have already been ...

Results: Single-cell analysis revealed distinct immune cell subtypes and indicated an increased presence of myeloid dendritic cells (mDCs) in patients with periodontal disease. MR analysis identified ...

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

Activation of the NFkB pathway contributes to the resistance to steroids, and its activation via TLR7 and 8 pathways, along with inhibition of plasmacytoid dendritic cell (pDC) apoptosis via TLR7, ...