Pluripotent stem cells are dynamic ... resulted in teratomas with different growth and differentiation characteristics 49. Liver teratomas were cystic, contained a mixture of immature and ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Pluripotent stem cells can provide a truly unlimited source for deriving therapeutically relevant cell types for applications in human disease modeling or regenerative medicine. A major effort of the ...

Our lab has pioneered the directed differentiation of human pluripotent stem cells into multiple specialized cell types of both the central and peripheral nervous system. The long-term goal is to ...

In the intricate science of reproduction, the creation of offspring has long relied on the union of sperm and eggs, whether ...

To address our questions we employ predominantly human pluripotent stem cell (hPSCs) differentiation as an in vitro model of early human embryonic development and utilise protocols we have recently ...

Pluripotent stem cells are known for the need to grow as colonies in order to prevent differentiation. This adds complexity to the isolation/expansion of clonal populations following research ...

Our laboratory focuses on understanding the mechanisms that control pluripotent stem cell self-renewal and commitment to differentiation. In particular, we investigate the molecular basis of ...

Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a ...