The proteasome is a large protein complex in the cytoplasm of eukaryotic and archaeal cells responsible for proteolysis of proteins that have one or more poly-ubiquitin post-translational ...

The intention is to move the two bispecifics earlier in the course of treatment, both alone and in combination with other drugs in the myeloma armamentarium, which includes proteasome inhibitors ...

a proteasome inhibitor, and an anti-CD38 antibody – setting up a full approval in the coming weeks. J&J filed for approval of the bispecific in the US in December based on the results of the ...

“I am pleased we have been able to recommend that this targeted treatment for a specific gene mutation ... including lenalidomide and a proteasome inhibitor. The approval covers Sarclisa's ...