Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas nonreceptor tyrosine kinases and serine/threonine protein kinases function throughout ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

One such strategy is to repurpose FDA-approved kinase ... CoV-2 is a protein that is found on the surface of the virus. ACE is an interferon-stimulated gene (ISG) that is expressed mostly in the ...

A research team revealed that insulin-like growth factor-binding protein 6 (IGFBP6) serves as a potential therapeutic target ...

Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

Lactate functions as a signaling molecule and interacts with a variety of protein ligands, including GPR132, GPR81, c-Jun, sAC, NDRG3, MAVS, and PHD2 ... a PTM that facilitates its interaction with ...

A new chemical compound has been making a big impression in the fight against cancer in recent years. Now it seems EBC-46, ...

If the loss of kidney function is severe, proteinuria may be a part of a more serious condition called nephrotic syndrome. This causes fluid buildup and dyslipidemia (unhealthy levels of cholesterol ...

A Deep Learning Toolkit for Protein Property Prediction, Localization Prediction, Protein-Protein Interaction, antigen epitope prediction, antibody paratope prediction, antibody developability ...

Proteins, essential molecular machines evolved over billions of years, perform critical life-sustaining functions encoded in their sequences and revealed through their 3D structures. Decoding their ...