This emphasizes the need to develop criteria that distinguish transcriptional noise from transcription with a biological function. In the classic view of the transcriptome, RNA polymerase ...

Another kind of RNA therapy that has been approved by regulators in the U.S. and Europe alike, are antisense oligonucleotides. These work by binding to specific mRNA sequences in order to modify gene ...

Researchers at the University of California at San Francisco have identified an RNA-binding protein that increased the translation of Myc mRNA. The authors wrote that their work, which was published ...

The platform’s scalability, rapid production and relatively straightforward manufacturing process mean that mRNA therapeutics are a powerful alternative to traditional small molecule drugs and DNA ...

InDevR partners with Aldevron to describe how the VaxArray 5′CapQ assay can be used to measure intact mRNA in a single assay to streamline bioprocess development.

Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid nanoparticles encapsulating messenger RNA (mRNA) to the immune system of ...

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Using a novel, RNA-based approach, we sought to restore this ... We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore ...

【导读】长链非编码RNA（lncRNAs）是胃癌（GC）发生发展过程中的关键调控因子，并可能成为潜在治疗靶点。1月29日，山东大学齐鲁医院及山东大学基础医学院研究团队共同在期刊《Cell ...

CREATE employs a modified L1 mRNA to carry a payload gene, and a Cas9 nickase to facilitate targeted editing by L1-mediated reverse transcription and integration without relying on ... Together, these ...

Aldevron, a global leader in the production of DNA, RNA and protein, has launched its latest innovation, Alchemy™ cell-free DNA technology. This revolutionary technology represents a significant ...