Announcing a new article publication for BIO Integration journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide, ...

A newly developed vaccine against a group of viruses including SARS-CoV-2 is producing promising results in mice, part of the ...

Ubiquitin-binding domains (UBDs) are modular elements that ... including protein stability, receptor trafficking, DNA damage responses and inflammatory pathways. UBD preferences for distinct ...

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Lastly, the Eph receptor SAM domain may recruit signaling partners ... would likely compensate for the low affinity of the SAM binding interaction. The structure of the EphA4 receptor SAM domain ...

They all share a mutation called N501Y that affects the receptor binding domain (RBD) of the spike protein, which the virus uses to clasp onto human cells’ receptors and enter them. That mutation ...

“We computationally predict what mutations allow better binding to host receptors and better evasion of antibodies,” said Boston College Assistant Professor of Biology Babak Momeni, a lead researcher ...

Traditional vaccines typically focus on the most accessible parts of viruses, which are often the rapidly mutating ...

Cys-loop receptors are ligand-gated ion channels ... interrupted the bottom domain's ability to feel the binding activity of the top domain. Like the sandy contents inside a child's magnetic ...