The interplay of mainly depressant and occasionally activating effects of alcohol creates chaos in the brain, leading to ...

By combining optogenetics—which uses light to control CIN activity—and fiber photometry—which involves genetically engineered biosensors to detect real-time release of acetylcholine while su ...

The Vagus Nerve’s Mysterious Role in Mental Health Untangled ...

Acetylcholine plays a vital role as a neurotransmitter that oversees cognitive tasks, memory, and the regulation of mood. With aging, our body’s generation of acetylcholine decreases, which ...

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several ...

Phase 3 AURORA trial of Descartes-08 in myasthenia gravis on track to commence in 1H25Deepening responses observed over time in ...

Zhenbo Huang, PhD, an associate research scientist in the laboratory of Jun Wang, MD, PhD, and colleagues have demonstrated that alcohol disrupts the brain’s ability to adapt by altering the ...

Nat Neurosci 2022). To their credit, the authors explicitly acknowledge this fact, but they believe that the only alternative possibility is that their intervention could lead to increased ...

Thus, acetylcholine modulates the encoding of surprising outcomes in the mPFC to control ... Although we stimulated cholinergic terminals in the PL, the stimulation could retrogradely activate their ...