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The EMBO Journal
6 天
RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Small GTPase RHEB is a well-known mTORC1 ...
生物通
6 天
耶鲁大学发表《Nature》:mTOR通路竟然与两种不同类型的罕见遗传病有关
研究小组还进行了几项分析,以评估类器官中基因和蛋白质的表达水平。他们的发现指出,在他们所研究的两种无脑畸形类器官中,mTOR(哺乳动物雷帕霉素靶点)通路都存在失调。 Louvi说:“这是控制细胞代谢的许多不同方面以维持细胞稳态的基本途径。
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