AlphaGalileo2h
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
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Mitochondria’s Secret Power Unleashed in the Battle Against Inflammation
Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...
Nature13d
NF-κB Signaling and T Cell Activation in Immune Responses
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a crucial signaling ... rheumatoid arthritis (RA), and certain cancers. Understanding how MALT1 influences T cell ...
Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis
Moreover, increased type I interferon signaling ... Rheumatoid arthritis (RA) is an autoimmune disease characterized by ...
Medscape16d
An Update on Methotrexate Pharmacogenetics in Rheumatoid Arthritis
Methotrexate (MTX) remains a cornerstone in the treatment of rheumatoid arthritis ... pathways, such as the folate and adenosine pathways involved in purine and pyrimidine metabolism within the cell.
WebMD2y
Lesson 6 of 8: Understanding Biologics
ALLAN GIBOFSKY: In rheumatoid arthritis ... or pathway in the inflammatory process they block. Many biologics target cytokines that can trigger inflammation or are responsible for signaling ...
technologynetworks13d
Targeting Mitochondria Function May Help Treat Inflammatory Diseases
Researchers revealed mitochondria's role in immune regulation through IL-10 production, controlled by mitochondrial complex ...
Mitochondria may be a promising therapeutic target for inflammatory diseases
Scientists in the laboratory of Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of ...