Deregulation in Rho GTPase signaling has been associated with all stages of cancer ... Formation of invadopodia involves a dramatic rearrangement of the actin cytoskeleton, a process that is regulated ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...

These toxins are known for their ability to modify Rho GTPases, which are proteins that regulate various cellular processes, including the organization of the cytoskeleton and cell signaling.

Eph-ephrin signaling is their cellular traffic light ... turning on Eph receptor forward signals that then target GEFs for Rho and GAPs for Rac and Cdc42 to produce GTP-bound Rho and GDP-bound ...

The cytoskeleton is a cellular scaffolding system whose functions include maintenance of cellular shape, enabling cellular migration, division, intracellular transport, signaling and membrane ...