Patients with systemic lupus erythematosus (SLE) who test positive for antiphospholipid antibodies (aPLs) are at a significantly higher risk of developing diffuse alveolar hemorrhage (DAH), according ...

Objectives The goals of these studies were to elucidate the inter-relationships of specific anti-nuclear antibody (ANA), complement, and the interferon gene signature (IGS) in the pathogenesis of ...

Anti-SS-B antibody is more specific for Sjögren’s disease. Anti-SS-A antibody is more likely with other autoimmune conditions, such as SLE and rheumatoid arthritis. Anti-SS-A antibodies can be present ...

[74] Accordingly, some clinical trials have been initiated in SLE, using monoclonal antibodies against IFN-α and its receptor (IFNAR) or using an immune therapy to induce polyclonal anti-IFN-α ...

LLPC may be harmful if they produce antibodies against self-proteins or self-nuclear antigens as occurs in autoimmune diseases such as systemic lupus erythematosus (SLE). Thus, the elimination of ...

We investigated whether activation of complement early in pregnancy predicts APOs in women with systemic lupus erythematosus (SLE) and/or antiphospholipid (aPL) antibodies. Methods The PROMISSE Study ...

Monoclonal antibodies (mAbs) and fusion (or chimeric ... This article focuses on anticytokine mAbs used as new therapeutic approaches in SLE. Other approaches (e.g., immune cell-based intervention ...

A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 ...

Lupus affects different people in different ways, and skin problems like rashes or sores re common. In a new study, people ...