Ferroptosis induces significant changes in mitochondrial morphology, including membrane condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting mitochondrial function ...

Methods: The effects of IFNβ on ferroptosis were analyzed in HT1080, 4T1, HCT116 and 786-O cells. HT1080 and 4T1 cells treated with IFNβ were subjected to RNA-Seq analysis. STAT1, STAT3, TRIM21, and ...

The study also raises the possibility of exploring the autophagy-ferroptosis axis in other cancers that metastasize to the bone. Dr. Aline Bozec, the lead investigator of the study, emphasized the ...

The study also raises the possibility of exploring the autophagy-ferroptosis axis in other cancers that metastasize to the bone. Dr. Aline Bozec, the lead investigator of the study, emphasized the ...

Ganzhou Municipal Key Laboratory of Bone and Joint Research, The Affiliated Ganzhou Hospital of Nanchang University, Meiguan Avenue No. 16, Ganzhou 341000, China The Affiliated Ganzhou Hospital of ...

The study also raises the possibility of exploring the autophagy-ferroptosis axis in other cancers that metastasize to the bone. Dr. Aline Bozec, the lead investigator of the study, commented ...

Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China ...

Get Instant Summarized Text (Gist) Autophagy, particularly through the protein ATG5, plays a crucial role in maintaining brain health by regulating glucose metabolism in neurons. In Purkinje cells ...

However, the molecular basis underlying the transformation from metaplastic to cancerous cells remains poorly understood. Conclusions Our findings highlighted that KLHL21 loss triggers STAT3 ...