[88] Liver disease ranges from mild elevation of the serum transaminases in asymptomatic individuals to chronic active hepatitis and cirrhosis. In certain circumstances, the initial presentation ...

High serum transaminases usually result from hepatocyte necrosis associated with acute viral infections, toxic or ischemic injury. By contrast, there is normal-to-moderate elevation of ...

Obtain urinalyses, serum electrolytes to evaluate renal tubular function. Measure serum transaminases, bilirubin before initiating therapy then every 2 weeks during 1 st month, then monthly.