Here, we provide an optimized approach for TCR clone selection that capitalizes on recent technological advances in the single-cell sequencing field that combine analysis of cellular heterogeneity of ...

The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which ...

Here, we provide an optimized approach for TCR clone selection that capitalizes on recent technological advances in the single cell sequencing field that combine analysis of cellular heterogeneity of ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

By integrating transcriptomic data, single-cell RNA sequencing data and ... function and developmental trajectory of myeloid precursor cells, but also screened out genes that are closely related to ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors ... aGPCR is that a ligand from outside the cell attaches to one of the extracellular ...

The different positions and movements of the extracellular region appear to be an important way to activate the receptor ... is that a ligand from outside the cell attaches to one of the ...

Ligand-receptor interactions play a key role in many biological functions, including cell metabolism and development, cell signaling, immune response, and tissue homeostasis. Consequently ...

To address this gap, researchers analyzed gene expression within individual tumor cells. This study reports the molecular features and interactions ... they utilized single-cell RNA sequencing ...